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Anderson DJ, Bunnelle W, Surber B, Du J, Surowy C, Tribollet E, Marguerat A, Bertrand D, Gopalakrishnan M (2008) JH]A-585539[(1S,4S)-2,2-dimethyl-5-(6-phenylpyridazin-3-yl)-5-aza-2-azoniabicyclo[2.2.1]heptane], a novel high-affinity alpha7 neuronal nicotinic receptor agonist: radioligand binding characterization to rat and human brain. J Pharmacol Exp Ther 324(1):179-187.

Breitling LP, Twardella D, Brenner H (2008) High effectiveness of short treatment with bupropion for smoking cessation in general care.Thorax 63:476-477.

Fehr C, Yakushev I, Hohmann N, Buchholz HG, Landvogt C, Deckers H, Eberhardt A, Kläger M, Smolka MN, Scheurich A, Dielentheis T, Schmidt L G, Rösch F, Bartenstein P, Gründer G, Schreckenberger M (2008) Association of low striatal dopamine d2 receptor availability with nicotine dependence similar to that seen with other drugs of abuse. AM J Psychiatry 165(4):507-514.

Breitling LP, Raum E, Müller H, Rothenbacher D, Brenner H (2008) Synergism between smoking and alcohol consumption with respect to serum gamma-glutamyltransferase. Hepatology 49(3):802-808.

Fregni F, Liguori P, Fecteau S, Nitsche MA, Pascual-Leone A, Boggio PS (2008) Cortical Stimulation of the Prefrontal Cortex With Transcranial Direct Current Stimulation Reduces Cue-Provoked Smoking Craving: A Randomized, Sham-Controlled Study. J Clin Psychiatry 69:32-40.

Gierke P, Zhao C, Bernstein HG, Noack C, Anand R, Heinemann U, Braunewell KH (2008) Implication of neuronal Ca2+-sensor protein VILIP-1 in the glutamate hypothesis of schizophrenia. Neurobiology of Disease 32:162–175.

Hoda JC, Gu W, Friedli M, Phillips HA, Bertrand S, Antonarakis SE, Goudie D, Roberts R, Scheffer IE, Marini C, Patel J, Berkovic SF, Mulley JC, Steinlein OK, Bertrand D (2008) Human nocturnal frontal lobe epilepsy: pharmocogenomic profiles of pathoge-nic nicotinic acetylcholine receptor beta-subunit mutations outside the ion channel pore. Mol Pharmacol 74(2):379-391.

Javitt DC, Spencer KM, Thaker GK, Winterer G, Hajós M (2008) Neurophysiological biomarkers for drug development in schizophrenia. Nat Rev Drug Discov 7(1):68-83.

Mobascher A, Winterer G (2008) Mechanismen der Nikotinahängigkeit/Mechanisms of nicotine dependence. Pneumologie 62(9):553-561.

Mobascher A, Winterer G (2008) The molecular and cellular neurobiology of nicotine abuse in schizophrenia. Pharmacopsychiatry 1:551-559.

Moreira FA, Lutz B (2008) The endocannabinoid system: emotion, learning and addiction. Addict Biol 13(2):196-212.

Rolls ET, Loh M, Deco G, Winterer G (2008) Computational models of schizophrenia and dopamine modulation in the prefrontal cortex. Nat Rev Neurosci 9(9):696-709.

Steinlein OK, Bertrand D (2008) Neuronal nicotinic acetylcholine receptors: from the genetic analysis to neurological diseases. Biochem Pharmacol 76(10):1175-1183.

Stefansson H, Rujescu D, Cichon S, Pietiläinen OP, Ingason A, Steinberg S, Fossdal R, Sigurdsson E, Sigmundsson T, Buizer-Voskamp JE, Hansen T, Jakobsen KD, Muglia P, Francks C, Matthews PM, Gylfason A, Halldorsson BV, Gudbjartsson D, Thorgeirsson TE, Sigurdsson A, Jonasdottir A, Jonasdottir A, Bjornsson A, Mattiasdottir S, Blondal T, Haraldsson M, Magnusdottir BB, Giegling I, Möller HJ, Hartmann A, Shianna KV, Ge D, Need AC, Crombie C, Fraser G, Walker N, Lonnqvist J, Suvisaari J, Tuulio-Henriksson A, Paunio T, Toulopoulou T, Bramon E, Di Forti M, Murray R, Ruggeri M, Vassos E, Tosato S, Walshe M, Li T, Vasilescu C, Mühleisen TW, Wang AG, Ullum H, Djurovic S, Melle I, Olesen J, Kiemeney LA, Franke B; GROUP, Sabatti C, Freimer NB, Gulcher JR, Thorsteinsdottir U, Kong A, Andreassen OA, Ophoff RA, Georgi A, Rietschel M, Werge T, Petursson H, Goldstein DB, Nöthen MM, Peltonen L, Collier DA, St Clair D, Stefansson K (2008) Large recurrent microdeletions associated with schizophrenia. Nature 455(7210):232-6.

Twardella D, Brenner H (2008) Implications of nonresponse patterns in the analysis of smoking cessation trials. Nicotine Tob Res 10(5):891-896.

Walsh H, Govind AP, Mastro R, Hoda JC, Bertrand D, Vallejo Y, Green WN (2008) Up-regulation of nicotinic receptors by nicotine varies with receptor subtype. J Biol Chem 283(10):6022-6032.

Wang-Sattler R, Yu Y, Mittelstrass K, Lattka E, Altmaier E, Gieger C, Ladwig KH, Dahmen N, Weinberger KM, Hao P, Liu L, Li Y, Wichmann HE, Adamski J, Suhre K, Illig T (2008) Metabolic profiling reveals distinct variations linked to nicotine consumption in humans--first results from the KORA study. PLoS ONE 3(12):e3863.

Von der Goltz C, Kiefer F (2008) Zur Bedeutung von Lernen und Gedächtnis in der Pathogenese von Suchterkrankungen. Der Nervenarzt 79(9):1006-1016.

Zhao C, Braunewell KH (2008) Expression of the neuronal calcium sensor visinin-like protein-1 in the rat hippocampus. Neuroscience 153:1202–1212.


Gallinat J, Lang UE, Jacobsen LK, Bajbouj M, Kalus P, Haebler VD, Seifert F, Schubert F (2007) Abnormal Hippocampal Neurochemistry in Smokers. J Clin Psychopharmacol 27:80–84.

Gu W, Bertrand D, Steinlein OK (2007) A major role of the nicotinic acetylcholine receptor gene CHRNA2 in autosomal dominant frontal lobe epilepsy (ADNFLE) is unlikely. Neurosci Lett 422:74-76.

Kiefer F (2007) The science of addiction: from neurobiology to treatment. Addiction 102(12):1990-1991.

Kuo MF, Grosch J, Fregni F, Paulus W, Nitsche MA (2007) Focusing Effect of Acetylcholine on Neuroplasticity in the Human Motor Cortex.The Journal of Neuroscience 27(52):14442–14447.

Lang N, Hasan A, Sueske E, Paulus W, Nitsche MA (2007) Cortical Hypoexcitability in Chronic Smokers? A Transcranial Magnetic Stimulation Study. Neuropsychopharmacology 1-7.

Lang UE, Sander T, Lohoff FW, Hellweg R, Bajbouj M, Winterer G, Gallinat J (2007) Association of the met66 allele of brain-derived neurotrophic factor (BDNF) with smoking. Psychopharmacology 190(4):433-439.

Monory K, Blaudzun H, Massa F, Kaiser N, Lemberger T, Schütz G, Wotjak CT, Lutz B, Marsicano G (2007) Genetic dissection of behavioural and autonomic effects of Delta(9)-tetrahydrocannabinol in mice. PLoS Biol 5(10):e269.

Musso F, Bettermann F, Vucurevic G, Stoeter P, Konrad A, Winterer G (2007) Smoking impacts on prefrontal attentional network function in young adult brains. Psychopharmacology 191(1):159-169.

Schmidt LG, Smolka MN (2007). Results from two pharmacotherapy trials show alcoholic smokers were more severely alcohol dependent but less prone to relapse than alcoholic non-smokers. Alcohol Alcohol 42:241-246.

Smolka MN, Bühler M, Schumann G, Klein S, Hu XZ, Moayer M, Zimmer A, Wrase J, Flor H, Mann K, Braus DF, Goldman D, Heinz A (2007) Gene-gene effects on central processing of aversive stimuli. Mol Psychiatry 12:307-317.

Twardella D, Brenner H (2007) Effects of practitioner education, practitioner payment and reimbursement of patients' drug costs on smoking cessation in primary care: a cluster randomised trial.Tob Control 16(1):15-21.

Winterer G, Musso F, Konrad A, Vucurevic G, Stoeter P, Sander T, Gallinat J (2007) Association of attentional network function with exon 5 variations of the CHRNA4 gene. Human Molecular Genetics 16(18):2165–2174.


Braunewell KH, Brackmann M, Hofmann A (2006) A Novel Regulator of the Guanylate Cyclase Transduction System in Neurons. Calcium Binding Proteins 1:12-15.

Diehl A, Nakovics H, Croissant B, Smolka MN, Batra A, Mann K (2006) Galantamine reduces smoking in alcohol-dependent patients: a randomized, placebo-controlled trial. International Journal of Clinical Pharmacology and Therapeutics 44:614-622.

Felten D, Raupach T, Sessler C, Lüthje L, Hasenfuß G, Andreas S (2006) Effektivität eines kognitiv-verhaltenstherapeutischen Raucherentwöhnungsprogramms mit pharmakologischer Unterstützung. Deutsch Med Wochenschrift 131:197-202.

Gallinat J, Meisenzahl E, Jacobsen LK, Kalus P, Bierbrauer J, Kienast T, Witthaus H, Leopold K, Seifert F, Schubert F, Staedtgen M (2006) Smoking and structural brain deficits: a volumetric MR investigation. European Journal of Neuroscience 24:1744–1750.

Kiefer F, Jahn H, Otte C, Naber D, Wiedemann K (2006) Hypothalamic-Pituitary-Adrenocortical Axis Activity:A Target of Pharmacological Anticraving Treatment?. Biol Psychiatry 60(1):74-76.

Lilla C, Verla-Tebit E, Risch A, Jäger B, Hoffmeister M, Brenner H, Chang-Claude J (2006) Effect of NAT1 and NAT2 genetic polymorphisms on colorectal cancer risk associated with exposure to tobacco smoke and meat consumption. Cancer Epidemiol Biomarkers Prev 15(1):99-107.

Must A, Spadano J, Coakley EH, Field AE, Colditz G, Dietz WH (2006) The Underestimated Impact of Smoking and Smoking Cessation on the Risk of Secondary Cardiovascular Disease Events in Patients With Stable Coronary Heart Disease: Prospective Cohort Study. JACC 47:884–892.

Neuhaus A, Bajbouj M, Kienast T, Kalus P, von Haebeler D, Winterer G, Gallinat J (2006) Persistent dysfunctional frontal lobe activation in former smokers. Psychopharmacology 186:191-200.

Raupach T, Schäfer K, Konstantinides S, Andreas S (2006) Secondhand smoke as an acute threat for the cardiovascular system: a change in paradigm. European Heart Journal 27:386–392.

Raupach T, Nowak D, Hering T, Batra A, Andreas S (2006) Rauchen und pneumologische Erkrankungen, positive Effekte der Tabakentwöhnung. Pneumologie 60:1-4.

Smolka MN, Bühler M, Klein S, Zimmermann U, Mann K, Heinz A, Braus DF (2006) Severity of nicotine dependence modulates cue-induced brain activity in regions involved in motor preparation and imagery. Psychopharmacology 184:577–588

Twardella D, Loew M, Rothenbacher D, Stegmaier C, Ziegler H, Brenner H (2006) The diagnosis of a smoking-related disease is a prominent trigger for smoking cessation in a retrospective cohort study. Journal of Clinical Epidemiology 59:82–89.

Twardella D, Loew M, Rothenbacher D, Stegmaier C, Ziegler H, Brenner H (2006) The impact of body weight on smoking cessation in German adults. Preventive Medicine 42:109–113.

Verla-Tebit E, Lilla C, Hoffmeister M, Brenner H, Chang-Claude J (2006) Cigarette smoking and colorectal cancer risk in Germany: A population-based case–control study. Int J Cancer 119:630–635.