A National Research Priority Program of  
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2012

Blum LC, van Deursen R, Bertrand S, Mayer M, Bürgi JJ, Bertrand D, Reymond JL (2012) Discovery of a α7-nicotinic receptor ligands by virtual screening of the chemical universe database GDB-13. J Chem Inf Model. 51(12):3105-12.

Bréthous L, Garcia-Delgado N, Schwartz J, Bertrand S, Bertrand D, Reymond JL (2012) Synthesis and nicotine receptor activity of chemical space analogues of N-(3R)-1-azabicylo[2.2.2]oct-3-yl-4-chlorobenzenamide (PNU-282,987) and 1,4-diazabicyclo[3.2.2]nonane-4-carboxylic acid 4-bromophenyl ester (SSR 180711). J Med Chem. 55(19):4605-18.

Bucerius J, Manka C, Schmaljohann J, Mani V, Gündisch D, Rudd JH, Bippus R, Mottaghy FM, Wüllner U, Fayad ZA, Biersack HJ (2012) Feasibility of [18F]-2-Fluoro-A85380-PET Imaging of human vascular nicotinic acetylcholine receptors in vivo. JACC Cardiovasc Imaging 5(5):528-36.

Cohrs S, Rodenbeck A, Riemann D, Szagun B, Jaehne A, Brinkmeyer J, Gründer G, Wienker T, Diaz-Lacava A, Mobascher A, Dahmen N, Thuerauf N, Kornhuber J, Kiefer F, Gallinat J, Wagner M, Kunz D, Grittner U, Winterer G (2012) Impaired sleep quality and sleep duration in smokers-results from the German Multicenter Study on Nicotine Dependence. Addict. Biol. 35(4):153-60.

Grundey J, Thirunganasambandam N, Kaminsky K, Drees A, Skwirba AC, Lang N, Paulus W, Nitsche M (2012) Neuroplasticity in Cigarette Smokers Is Altered under Withdrawal and Partially Restituted by Nicotine Exposition. The Journal of Neuroscience, 32(12):4156-4162.

Grundey J, Thirugnanasambandam N, Kaminsky K, Drees A, Skwirba AC, Lang N, Paulus W, Nitsche MA (2013) Rapid effect of nicotine intake on neuroplasticity in non-smoking humans. Front Pharmacol. 3:186.

Kühn S, Romanowski A, Schilling C, Mobascher A, Warbrick T, Winterer G, Gallinat J (2012) Brian grey matter deficits in smokers: focus on the cerebellum. Brain Structure Function 217:517-22.

Lenz B, Klafki HW, Hillemacher T, Frieling H, Clepce M, Gossler A, Thuerauf N, Winterer G, Kornhuber J, Bleich S (2012) ERK 1/2 protein and mRNA levelos in human blood are linked to smoking behavior. Addict Biol. 7(19):e47785.

Luckhaus C, Henning U, Ferrea S, Musso F, Mobascher A, Winterer G (2012) Nicotinic acetylchlorine receptor expression on B-lymphoblasts of healthy versus schizophrenic subjects stratified for smoking: [3H]-nicotine binding is decreased in schizophrenia and correlates with negative symptoms. J Neural Transm. 119(5):587-95.

Mihov Y, Hurlemann R (2012) Altered amygdala function in nicotine addiction: insights from human neuroimaging studies. Neuropsychologia 50(8):1719-29.

Mobascher A, Warbrick T, Brinkmeyer J, Musso F, Stoecker T, Jon Shah N, Winterer G (2012) Nicotine effects on anterior cingulate cortex in schizophrenia and healthy smokers as revealed by EEG-informed fMRI. Psychiatry Res. 204(2-3):168-77.

Mutschler J, Abbruzzese E, von der Goltz C, Dinter C, Mobascher A, Thiele H, Diaz-Lacava A, Dahmen N, Gallinat J, Majic T, Petrovsky N, Kornhuber J, Thuerauf N, Gründer G, Brinkmeyer J, Wienker T, Wagner M, Winterer G, Kiefer F (2012) Genetic variation in the neuropeptide Y gene promoter is associated with increased risk of tobacco smoking. Eur Addict Res. 18(5):246-52.

Onur OA, Patin A, Mihov Y, Buecher B, Stoffel-Wagner B, Schlaepfer TE, Walter H, Maier W, Hurlemann R (2012) Overnight deprivation from smoking disrupts amygdala responses to fear. Hum Brain Mapp. 33(6):1407-16.

Petrovsky N, Ettinger U, Quednow BB, Walter H, Schnell K, Kessler H, Mössner R, Maier W, Wagner M (2012) Nicotine differentially modulates antisaccade performance in healthy male non-smoking volunteers stratified for low and high accuracy. Psychopharmacology 221(1):27-38.

Quednow BB, Brinkmeyer J, Mobascher A, Nothnagel M, Musso F, Gründer G, Savary N, Petrovsky N, Frommann I, Lennertz L, Spreckelmeyer KN, Wienker T, Dahmen N, Thuerauf N, Clepce M, Kiefer F, Majic T, Mössner R, Maier W, Gallinat J, Díaz-Lacava A, Toliat MR, Thiele H, Nürnberg P, Wagner M, Winterer G (2012) Schizophrenia risk polymorphisms in the TCF4 gene interact with smoking in the modulation of auditory sensory gating. Proc Natl Acad Sci USA 109(16):6271-6.

Warbrick T, Mobascher A, Brinkmeyer J, Musso F, Stoecker T, Shah J, Winterer G (2012) Using single trial EEG-fMRI to investigate nicotine effects on brain and behavioural responses to a visual oddball task. J Cogn Neuroscii. 24(8):1682-94.

Warbrick T, Mobascher A, Brinkmeyer J, Musso F, Stoecker T, Shah NJ, Fink GR, Winterer G (2012) Nicotine effects on brain function during a visual oddball task: a comparison between conventional and EEG-informed fMRI analysis. J Cogn Neurosci. 24(8):1682-94.